
The Monarch kits enable quick and easy purification of high-quality DNA and RNA that is suitable for a variety of downstream applications. These include electrophoresis, transformation, PCR and qPCR, as well as NGS library preparation.
The popular Monarch nucleic acid purification kits are now available in an upgraded version. Columns and kits are redesigned using significantly less plastic for reduced environmental impact. Components of the new kits, such as buffers and columns, are also available separately. This makes it easy to replenish the kit if something runs out.
Column design in the upgraded kits has been optimized to prevent buffer retention and salt carry over. The column is designed and made with less plastic to reduce environmental impact.

NEW! - Monarch Spin High-Capacity DNA Cleanup Kit (100 µg) -T1135
- Purify up to 100 µg of DNA, and elute in just 50 µl for highly concetnrated DNA
- New precision-engineered spin columns, helps prevent buffer retention and salt carryover
- Modified protocol provided for oligonucleotide, genomic DNA, or RCA products
- Kit sizes 10 preps, 50 preps and 200 preps
Monarch Spin Plasmid Miniprep kit - T1110
- Easily purify plasmids with convenient colored buffer system
- Elute in as little as 30 μl for highly concentrated DNA, with yields up to 20 μg
- Colored buffer system for easy to follow workflow
- Short and fast protocols
- Kits are made with less plastic with redesigned columns and bottles
- Kit sizes 50 preps and 250 preps
- Replaces kit T1010
Monarch Spin DNA Gel Extraction kit - T1120
- Extract excellent DNA yields
- Elute in as little as 5 μl for highly concentrated DNA, with yields up to 5 μg
- No need to monitor pH or add isopropanol
- Faster protocols and less spin time
- Kit sizes 50 preps and 250 preps
- Replaces kit T1020
Monarch Spin PCR & DNA Cleanup kit - T1130
- Purify DNA in 5 minutes
- Elute in as little as 5 μl for highly concentrated DNA, with yields up to 5 μg
- No need to monitor buffer pH
- Protocol modification for oligonucleotide cleanup is provided, allowing purification of ssDNA, oligonucleotide and other small DNA fragments
- Kit sizes 50 preps and 250 preps
- Replaces kit T1030
Monarch Spin RNA Isolation Kit (Mini) - T2110
- Purify RNA from multiple sample types, such as cultured cells, tissue, microbes, and plants
- Elute in as little as 10 µl
- Purified RNa suitable for downstream applications such as RT-qPCR, cDNA synthesis, and RNA-seq
- Kit size 50 preps
Monarch Spin gDNA Extraction Kit - T3010
- Purify high-quality, genomic DNA from several sample types, such as cells, blood, tissue, bacteria, yeast, saliva, swabs with just this single kit
- Achieve excellent DNA yields with fast, user-friendly protocols
- Kit sizes 50 preps and 150 preps
Monarch HMW DNA Extraction Kit for Cells & Blood - T3050
- Quickly and easily extract ultra-high molecular weight DNA from cells and blood
- Kit sizes 5 preps and 50 preps
Monarch HMW DNA Extractin Kit for Tissue - T3060
- Achieve DNA from tissue samples in the megabase size range
- Kit sizes 5 preps and 50 preps
Monarch Spin RNA Cleanup Kits (10, 50, 500 µg) - T2030, T2040, T2050
- Purify and concentrate RNA after enzymatic reactions and RNA synthesis
- Choose between 3 convenient binding capacities (10 µg, 50 µg, and 500 µg)
- Kit sizes 10 preps and 100 preps
Monarch Mag Viral DNA/RNA Extraction Kit - T4010
- Enables reliable, high-throughput purification of viral nucleic acid using a magnetic bead-based protocol
- Compatible with manual and automated high-throughput workflows on a variety of instrument platforms
- Suitable for qPCR/RT-qPCR, ddPCR, library prep for sequencing/NGS and other downstream applications
- Kit sizes 10 preps, 600 preps and 3x600 preps
Advantages of Monarch kits
Highly Pure DNA
Monarch DNA Purification Kits are designed to provide the purest DNA with minimal contaminants. This is crucial for downstream applications and reliably ensures higher cloning efficiency and accuracy.

Highly Concentrated DNA
Precision-engineered spin columns uniquely allow for low elution volumes, for highly concentrated DNA to be used downstream in NEBuilder HiFi DNA Assembly, NEBridge Golden Gate Assembly, and traditional cloning workflows.

Fast Protocols
The protocols for Monarch kits are optimized to be quick and user-friendly, ensuring that DNA is ready for use without extensive preparation. This saves time and reduces the risk of sample loss or degradation

Kits for the Whole Workflow
NEB has all your workflow needs covered with kits for Plasmid Purification, Gel Extraction, PCR and DNA Cleanup, and Genomic DNA Extraction

Sustainability and Value
Monarch kits are designed for industry-leading sustainability, using less plastic and recyclable packaging, while still being better for your budget. Feel good about helping the environment without compromising on performance or price.
