Our Suppliers for Organoid Study
Organoids are exciting models that are rapidly becoming a hopeful platform for many medical advances such as drug screening and disease modeling. As miniature versions of organs, organoids closely mimic the architecture, cellular composition, and functions of their full-sized counterparts. These 3D cell cultures are derived from pluripotent stem cells (PSCs), adult stem cells, or tissue-specific cells and are encouraged to self-organize into structures that replicate the complexity of actual organs. Organoids encapsulate intricate cellular interactions, tissue-specific functions, and some disease behaviors, making them invaluable tools for studying human physiology and pathology in a controlled environment.
Assay Genie - Cell Viability
Quantitative colorimetric 3D Organoid Cell Viability Assay
With this Assay Genie´s assay, you can accurately measure the number of live cells in both 2D and 3D organoid models.The assay is validated by using apical-out airway organoids and neuronal organoids. The assay is a 1-Step, no wash assay, ie. a simple test using one reagent. This assay exhibits significantly lower cytotoxicity compared to other reagents like MTS, MTT, or PrestoBlue. Assess cell viability, growth, or cytotoxic effects over a time range of 1 to 48 hours.
- For 100 tests AG-AKES081-100
- For 500 tests AG-AKES081-500
Qkine - Growth Factors
Given the longer culture time of organoids compared to traditional cell culture, it is crucial to ensure that all growth factors used in organoid cultures maintain consistent biological activity. To enhance reproducibility and facilitate larger-scale production, consider substituting conditioned media with recombinant proteins-like high-purity R-spondin 1 and noggin. BioNordika’s partner Qkine offers a complete portfolio of animal- and carrier protein-free growth factors and cytokines for organoid culture.
ACROBiosystems - Organoid Solutions
Ready-to-use Organoids
iPSC-derived organoids prepared for immediate experiments.
- Cerebral Organoids
- Cardiac Organoids
- Intestinal Organoids
- Liver Organoids
Organoid Differentiation Kits
Differentiation kits simplify the process of transforming iPSCs into specific organoids. They include instructions, and all reagents for successful differentiation process.
- Cerebral Organoids
- Cardiac Organoids
- Intestinal Organoids
- Liver Organoids
- Differentiation Kits
Organoid Culture Reagents
Acro Biosystems provides a selection of cytokines that are specifically formulated for optimal organoid culture, ensuring that your organoids receive the right signals for proper growth and differentiation. The Mogengel matrix is a three-dimensional culture substrate that supports organoid development. It mimics the extracellular matrix found in living organisms, promoting crucial interactions between cells and their environment.
- Cytokines for Organoid Culture (EGF, Noggin, R-Spondin 1, BDNF)
- Mogengel Matrix for Organoid Culture
Antibodies for Organoid Identification
Antibodies are crucial for tracking cell differentiation and evaluating the functional status of organoids. Acro Biosystems provides highly specific and sensitive antibodies, allowing for accurate detection of neural markers in cerebral organoids.
- Neuron Marker Antibody
- Glial Marker Antibody
- Vascular Marker Antibody
iPSC-differentiated Cells
Cells generated from reprogrammed somatic cells can develop into different cell types, aiding in disease research and treatment. Acro Biosystems portfolio includes the following cell types:
- Neuronal Precursors
- Dopaminergic Neurons
- Motor Neurons
- Cardiomyocytes
Organoid Services
Organoid services include organoid creation, disease modeling, and testing services.
ACROBiosystems - Kit Information
Cerebral organoids & differentiation kits
- AB-CIPO-BWL001K Ready-to-use Human iPSC-Derived Cerebral Organoids
- AB-CIPO-BWL001KC Cryopreserved Human iPSC-Derived Cerebral Organoids
- AB-RIPO-BWM001K Human iPSC-Derived Cerebral Organoid Differentiation Kit
- AB-RIPO-BWM003 Human iPSC-Derived Cerebral Organoid Maturation and Maintenance Kit
- AB-RIPO-BWM006 Cerebral Organoid Cryopreservation Kit
Cardiac Organoids & Differentiation Kits
- AB-CIPO-HWL002K Ready-to-use Human iPSC-Derived Cardiac Organoids
- AB-RIPO-HWM002K Human iPSC-Derived Cardiac Organoid Differentiation Kit
- AB-RIPO-HWM004 Human iPSC-Derived Cardiac Organoid Maintenance Kit
- AB-RIPO-HWM005 Cardiac Organoid Cryopreservation Kit
Intestinal Organoids & Differentiation Kits
- AB-CIPO-IWL003K Ready-to-use Human iPSC-Derived Intestine Organoids
- AB-RIPO-IWM005K Human iPSC-Derived Intestinal Organoid Differentiation Kit
- AB-RIPO-IWM006 Human iPSC-Derived Intestinal Organoid Maintenance Kit
Liver Organoids & Differentiation Kits
- AB-CIPO-RWL005K Ready-to-use Human iPSC-Derived Liver Organoids
- AB-RIPO-RWM009K Human iPSC-Derived Liver Organoid Differentiation Kit
- AB-RIPO-RWM010 Human iPSC-Derived Liver Organoid Expansion and Maintenance medium
iPSC-differentiated Cells
- AB-CIPC-NWC001 Human iPSC-Derived Neural Progenitor Cells
- AB-CIPC-NDC001 Human iPSC-Derived Neural Progenitor Cells (Parkinson's disease)
- AB-CIPC-DWC001 Human iPSC-Derived Dopamine Neurons
- AB-CIPC-DDC001 Human iPSC-Derived Dopamine Neurons (Parkinson's disease)
- AB-CIPC-CWC001 Human iPSC-Derived Ventricular Cardiomyocytes
- AB-CIPC-CWC002 Human iPSC-Derived Ventricular Cardiomyocytes
Greiner Bio-One - Magnetic 3D Cell Culture Technology
Greiner-Bio’s NanoShuttle-PL uses magnetic forces to aggregate cells with levitation or printing. This technology forms structurally and biologically representative 3D models in vitro.
Levitation - 6 and 24 well
By levitating cells from the bottom of a cell-repellent plate, magnetic forces work as an invisible scaffold to gently and rapidly aggregate cells. This forms larger spheroids at the air-liquid interface, induces cell-cell interactions, and initiates ECM synthesis.
Bioprinting - 96, 384 and 1536 well
NanoShuttle-PL allows bioprinting of magnetized cells into spheroids. This is done by placing a cell repellent plate atop a drive of magnets, where a single magnet below each well utilizes mild magnetic forces to induce aggregation and print one spheroid at the bottom of each well. This takes approximately 15 minutes to a few hours.
Bio Assay - 96 and 384 well
For bioassays, cells can printed into a ring formation. After printing the patterned structures will shrink/close as a function of cell migration, viability, cell-cell interaction, and/or proliferation. The structures will stay for up to 72 hours following bioprinting.
